BARRY L. WENIG, MD, MPH; GREGORY S. BUSSELL, MD
CHICAGO, ILLINOIS
Surgery or radiotherapy results in cure rates greater than 80% for early-stage
supraglottic laryngeal tumors. In this paper, we evaluate the feasibility
of supraglottic laryngectomy in place of total laryngectomy for irradiation
failures. We performed a retrospective review of 478 patients with an original
diagnosis of supraglottic laryngeal cancer. Seventy-seven (16.1%) were
treated with radiotherapy for cure. Of the 77 patients treated by irradiation
alone, 21(27.3%) failed either at the primary site or in the neck. Among
those who failed radiotherapy, 15 (71.4%) were treated by salvage total
laryngectomy with or without neck dissection, while the remaining 6(28.6%)
were treated by supraglottic laryngectomy with or without neck dissection.
Of these, 4 are alive and free of disease. Meticulous surgical technique
is essential in order to successfully perform the surgery. Supraglottic
laryngectomy should be considered as an alternative to total laryngectomy
as a salvage procedure for irradiation failure of early supraglottic cancers.
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