Donald T. Weed, MD, Brian S. Jewett, MD, Cheryl Rainey,
MS
David L. Zealear, PhD, R.E. Stone, PhD, Robert H. Ossoff, DMD, MD
James L. Netterville, MD
Long-term follow-up of 3 to 7 years is reported on 18 patients who had
undergone recurrent laryngeal nerve avulsion (RLNA) for the treatment of
adductor spastic dysphonia (SD). Data on neural regrowth after previous
recurrent laryngeal nerve section (RLNS) are presented in 2 of these 18
patients. We introduced RLNA as a modification of standard RLNS to prevent
neural regrowth to the hemiparalyzed larynx ant subsequent recurrence of
SD. We have treated a total of 22 patients with RLNA, and now report a
3- to 7-year follow-upon 18 of these 22 patients. Resolution of symptoms
was determined by routine follow-up assessment, perceptual voice analysis,
and patient self-assessment. Sixteen of 18, or 89*, had no recurrence of
spasms at 3 years after RLNA as determine at routine followup. Two of the
16 later developed spasms after medialization laryngoplasty for treatment
of weak voice persistent after the avulsion. This yielded a total of 14
of 18, or 78%, who were unanimously judged by four speech pathologists
to have no recurrence of SD at the longer follow-tip period of 3 to 7 years.
Two of these 4 patients were judged by all four analysts to have frequent,
short spasms. The other 2 were judges by two of four analysts to have seldom,
short spasms. Three of 18 patients presented with recurrent SD after previous
RLNS. At the time of subsequent RLNA, each patient hat evidence of neural
regrowth at the distal nerve stump as demonstrated by intraoperative electromyography
and histologic evaluation of the distal nerve stump. One remained free
of SD following RLNA, 1 was free of spasms at 4 years after revision avulsion
but developed spasms after medialization laryngoplasty, and the foal patient
developed spasms 3.75 years after revision RLNA. Medialization laryngoplasty
with Silastic silicone rubber was performed in 6 of 18, with correction
of postoperative breathiness in all 6, but with recurrence of spasm in
3. Spasms resolved in 1 of these with downsizing of the implant. We conclude
that RLNA represents a useful treatment in the management of SD in patients
not tolerant of botulinum toxin injections. |